The work is dedicated to the study of the joint variability of somatic characteristics and level of sex hormones (estradiol and testosterone), as well as to the assessment of anthropometric indicators and steroid profile in Moscow students. The material of the study is represented by comprehensive anthropological survey of 152 people (18–22 year old): 122 females (average age — 19.9 years) and 30 males (average age — 20.2 years) of Moscow higher educational institutions. The analysis included data from respondents of Russian nationality permanently residing in Moscow and nearest Moscow region. The examination program included the measurement of total body sizes, the assessment of body composition, BMI, waist-to-hip ratio (WHR), sexual dimorphism index (by Tanner); indicators of the relative value of body components were calculated as well. In addition, the hormonal profile of the participants was obtained (total testosterone and total estradiol levels in blood serum), on the basis of which the estradiol-testosterone ratio (E/T) was calculated. The analysis of morphophysiological characteristics of modern Moscow young people revealed the presence of reliable correlations (r = 0.2–0.3) between hormonal production and soma parameters only in girls: estradiol is negatively associated with waist circumference and positively with the proportion of active cell mass (a direct relationship with it was also found in the E/T ratio). The level of testosterone secretion is positively associated with the value of the sexual dimorphism index. The results of factor analysis reveal a consistent variability in the levels of sex steroids with morphological parameters: estradiol is associated with indicators of obesity, and testosterone — with the proportion of musculoskeletal mass and the value of sexual dimorphism. The revealed features of the shared variation of morphophysiological signs are characteristic for both sexes, which indicates their stability and biological regularity. Increased testosterone secretion was recorded for 15.6 % of female students. The average values of morphological indicators in this group significantly differ from individuals with normal hormone secretion towards the increasing andromorphism of the physique (due to an increase in the proportion of musculoskeletal mass and the value of sexual dimorphism index). It can be assumed that these results indicate an increased stress load within the metropolitan region.